Cytopoint 30mg Solution for Injection for Dogs
Cytopoint 30mg is a revolutionary prescription biological therapy specifically developed for dogs suffering from allergic dermatitis and atopic dermatitis. Manufactured by Zoetis, this ready-to-use sterile injectable solution contains lokivetmab, a caninized monoclonal antibody (mAb) that targets and neutralizes interleukin-31 (IL-31) – the key cytokine responsible for transmitting itch signals to the brain.
Unlike traditional steroids or immunosuppressive drugs, Cytopoint works with your dog’s own immune system to provide targeted, long-lasting relief from pruritus (itching). A single subcutaneous injection administered by a veterinarian can deliver 4 to 8 weeks of comfort, allowing damaged skin to heal while breaking the destructive itch-scratch cycle.
Key Features
- Targeted Action: Specifically binds to and neutralizes canine IL-31, the primary itch-inducing protein in allergic skin disease.
- Rapid Onset: Many dogs experience noticeable itch relief within 24 hours (some as early as 8 hours).
- Long Duration: One injection typically provides 4–8 weeks of continuous relief, reducing the need for daily medication.
- Steroid-Free: Not a corticosteroid or conventional immunosuppressant – ideal for long-term management.
- Safe for Most Dogs: Suitable for dogs of all ages (minimum 3 kg body weight) and can be used alongside many other medications and in dogs with concurrent diseases.
- Convenient Administration: Single subcutaneous injection given in-clinic by a veterinarian – no daily pills required at home.
- Minimal Organ Burden: Eliminated through normal protein degradation pathways with little involvement of the liver or kidneys.
How Cytopoint Works
Atopic dermatitis and allergic dermatitis cause dogs to produce excess IL-31, which binds to receptors and sends powerful itch signals to the brain. This leads to relentless scratching, licking, chewing, and rubbing that damages the skin barrier and often results in secondary infections.
Cytopoint’s monoclonal antibody circulates in the bloodstream and specifically captures IL-31 before it can trigger the itch response. By interrupting this pathway, the injection rapidly reduces pruritus and gives the skin a chance to recover. It does not cure the underlying allergy but effectively manages the most distressing clinical sign – the itch.
Indications
- Treatment of clinical manifestations of atopic dermatitis in dogs
- Control of pruritus associated with allergic dermatitis
- Supportive management of chronic or seasonal allergic skin disease
Dosage & Administration
Cytopoint is supplied as a 1 ml single-use vial containing 30 mg of lokivetmab. The recommended minimum dose is 1–2 mg/kg body weight (depending on local labelling). The 30 mg strength is typically suitable for dogs weighing approximately 15–30 kg (or 20–30 lb in some markets).
Administer the entire contents of the vial subcutaneously. For larger dogs, multiple vials may be combined. Repeat every 4–8 weeks as determined by the individual patient’s response. Do not use in dogs weighing less than 3 kg.
Benefits for Dogs & Owners
- Breaks the itch-scratch cycle so skin can heal
- Improves quality of life for both dog and family
- Reduces caregiver burden compared with daily oral medications
- Can be used long-term under veterinary supervision
- Compatible with many concurrent treatments (antibiotics, antifungals, other allergy therapies)
Important Safety Information
Cytopoint has an excellent safety profile. The most commonly reported side effects are mild and transient (lethargy, vomiting, or diarrhoea). Monitor dogs for secondary bacterial skin infections, especially in the first weeks of treatment. Do not use in cases of known hypersensitivity to the active substance or any excipient.
Prescription only. This product must be administered by a veterinarian. Always follow your vet’s advice regarding diagnosis, dosing interval, and monitoring.
Storage
Store refrigerated between 2–8 °C. Do not freeze. Protect from light. Use immediately after opening; discard any remaining product.
Give your dog lasting comfort from allergic itch with Cytopoint 30mg – the targeted, long-acting solution trusted by veterinarians worldwide.