Cytopoint 40mg

Cytopoint 40mg Solution for Injection for Dogs – Targeted Relief from Allergic Itch

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Cytopoint 40mg is a pioneering veterinary biological therapy containing lokivetmab, a caninised monoclonal antibody specifically designed to treat pruritus (itching) associated with allergic dermatitis and the clinical signs of atopic dermatitis in dogs. Manufactured by Zoetis, this ready-to-use sterile injectable solution provides fast, long-lasting itch relief with a single subcutaneous injection administered by a veterinarian.

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How Cytopoint Works

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Cytopoint targets and neutralises interleukin-31 (IL-31), a key cytokine that transmits the itch signal to the brain in dogs suffering from allergic skin disease. By blocking IL-31 before it can bind to its receptor, Cytopoint interrupts the itch-scratch cycle at its source. Unlike steroids or broad immunosuppressants, it acts with precision and does not suppress the overall immune system.

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• Onset of action: as early as 8 hours after injection
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• Duration of relief: up to 4–8 weeks with a single dose
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• Convenient monthly administration under veterinary supervision
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Key Benefits

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• Targeted biological therapy – specifically engineered for dogs
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• Rapid itch control – reduces scratching, licking, chewing and rubbing
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• Long-lasting effect – one injection can provide a full month of relief
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• Excellent safety profile – well tolerated in dogs of various ages (minimum 3 kg body weight)
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• Compatible with many concurrent medications and can be used alongside management of secondary infections or allergen control
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• Helps break the itch-scratch cycle, allowing damaged skin to heal
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Indications

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Cytopoint 40mg is indicated for:

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• Treatment of pruritus associated with allergic dermatitis in dogs
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• Treatment of clinical manifestations of atopic dermatitis in dogs
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Composition

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Each 1 ml vial of Cytopoint 40mg contains:

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• Active substance: Lokivetmab 40 mg (caninised monoclonal antibody produced in Chinese Hamster Ovary cells)
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• Excipients: Histidine, histidine hydrochloride monohydrate, trehalose dihydrate, disodium edetate, methionine, polysorbate 80, water for injections
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Clear to opalescent solution, free from visible particles. Preservative-free. Single-use vials only.

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Dosage and Administration

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For subcutaneous use only. The recommended minimum dose is 1 mg/kg body weight once a month (some regions use a 2 mg/kg minimum). Administer the entire contents of the vial(s). Avoid excessive shaking.

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Dosing guide for Cytopoint 40mg (approximate):

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Repeat treatment monthly or as clinically required based on the individual dog’s response and veterinary assessment. Do not use in dogs under 3 kg.

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Storage

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• Store refrigerated at 2°C – 8°C
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• Do not freeze
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• Protect from light
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• Keep in original packaging
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• Use immediately after opening; discard any unused portion
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Important Safety Information

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Most dogs tolerate Cytopoint very well. Rare side effects may include hypersensitivity reactions (facial swelling, urticaria, anaphylaxis), vomiting, diarrhoea, lethargy or injection-site reactions. Seek immediate veterinary attention if serious reactions occur. Not recommended for use in breeding, pregnant or lactating bitches unless the benefit outweighs the risk. Always follow your veterinarian’s advice and prescription.

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Prescription required. Cytopoint must be administered by a veterinary professional. This product is intended for dogs only.

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Give your dog the comfort they deserve with Cytopoint – targeted, effective and long-lasting relief from allergic itch.