Zylexis – Advanced Non-Specific Immunomodulator for Companion and Farm Animals
Zylexis is a premium veterinary immunomodulator containing inactivated Parapoxvirus ovis (strain D1701). It acts as a powerful super-antigen that rapidly stimulates the innate immune system without causing disease. Trusted by veterinarians worldwide and manufactured by Zoetis, Zylexis provides fast-acting support for the prevention and treatment of infectious and stress-induced diseases in dogs, cats, horses, cattle and pigs.
Key Features
- Rapid onset of action – immune stimulation begins within a few hours to 2 days
- Duration of effect – approximately 10–14 days after the last injection
- Supports non-specific immunity by activating natural killer cells, stimulating lymphocyte proliferation, activating macrophages and inducing antiviral interferons and interleukins (IL-6, IL-12, TNF-α)
- Proven to reduce clinical symptoms in respiratory herpesvirus infections (horses & cattle), feline calicivirus infections, and crowding-associated respiratory/enteric diseases
- Safe for use from the first day of life, in pregnant and lactating animals
- Available as lyophilisate + sterile diluent for easy reconstitution
Indications
Zylexis is indicated as an aid in the prevention and treatment of infectious and/or stress-induced diseases by stimulating non-specific immune mechanisms in:
- Dogs
- Cats
- Horses
- Cattle
- Pigs
Particularly useful during periods of high infection pressure, stress (transport, competition, crowding, weaning) or as concurrent therapy to accelerate recovery.
Composition (per 1 ml reconstituted product)
- Inactivated Parapoxvirus ovis, strain D1701 – ≥1 RP (relative potency) or min. 230 IFN units
- Stabilizer L2
- Water for injections
Dosage & Administration
| Species |
Dose |
Route |
| Dogs & Cats |
1 ml |
Subcutaneous (SC) |
| Horses, Cattle & Pigs |
2 ml |
Intramuscular (IM) |
Recommended schedule (3 doses):
- When infection/stress expected within 7 days: Day 0, Day 2, Day 4
- When infection/stress expected within 14 days: Day 0, Day 2, Day 9
- For prophylaxis: first dose preferably 1–3 days before the stressful event
Reconstitute the lyophilisate aseptically with the provided diluent immediately before use. Shake gently until fully dissolved. Use sterile syringes and needles. Once reconstituted, use within 8 hours if stored at 2–8°C.
Storage
Store in a refrigerator at 2–8°C. Do not freeze. Protect from light. Keep out of reach of children.
Why Choose Zylexis?
When your animals face stress or infection risk, Zylexis delivers a rapid, broad-spectrum immune boost that helps reduce the severity and duration of clinical signs. Ideal for kennels, catteries, stables, farms and individual pet owners seeking professional-grade immune support. Always use under veterinary supervision.
Prescription-only veterinary medicinal product in most countries. Consult your veterinarian for advice tailored to your animal.