Apoquel 16mg Tablets 100

Apoquel 16mg Tablets for Dogs – Fast, Targeted Relief from Allergic Itch\n

Apoquel (oclacitinib maleate) 16mg tablets are a prescription veterinary medicine designed specifically for dogs. This innovative Janus Kinase (JAK) inhibitor provides rapid and effective control of pruritus (itching) associated with allergic dermatitis and the clinical manifestations of atopic dermatitis in dogs 12 months of age and older.

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Unlike traditional steroids or antihistamines, Apoquel works by selectively targeting the key cytokines responsible for itch and inflammation, delivering relief that starts within 4 hours and achieves control within 24 hours. It is one of the most prescribed oral medications for allergic itch in dogs worldwide.

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Key Features & Benefits

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• Fast-acting relief – Begins reducing allergic itch in as little as 4 hours
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• Effective control – Significantly reduces itching and inflammation within 24 hours
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• Targeted action – Selectively inhibits JAK1 enzymes involved in pruritogenic and pro-inflammatory cytokines
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• Flexible use – Suitable for short-term flare control or long-term maintenance therapy
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• Convenient dosing – Can be given with or without food
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• Scored tablets – Easy to split for precise dosing
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• Proven safety profile – Extensively studied for both short- and long-term use in dogs
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Indications

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Apoquel is indicated for:

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• Control of pruritus (itching) associated with allergic dermatitis in dogs
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• Control of clinical manifestations of atopic dermatitis in dogs
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It is intended for dogs at least 12 months of age and weighing a minimum of approximately 3 kg.

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Active Ingredient

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Each film-coated tablet contains 16 mg oclacitinib (as oclacitinib maleate).

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How Apoquel Works

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Oclacitinib is a selective JAK inhibitor. It blocks the signaling pathways of cytokines such as IL-31 (the primary itch cytokine), IL-2, IL-4, IL-6, and IL-13 that drive allergic itch and inflammation. By targeting these specific pathways, Apoquel provides rapid itch relief with minimal impact on broader immune function compared to corticosteroids.

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Dosage & Administration

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The recommended dose is 0.4 to 0.6 mg oclacitinib per kg body weight.

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• Initial therapy: Twice daily for up to 14 days
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• Maintenance therapy: Once daily thereafter, based on individual response and veterinary assessment
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Administer orally with or without food. Ensure the tablet is fully swallowed. Tablets are scored and can be divided into equal halves.

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Approximate Dosing Guide for 16 mg Tablets

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*Exact dosing should always be confirmed by your veterinarian using the full dosing chart that includes 3.6 mg and 5.4 mg strengths for precision.

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Important Safety Information

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• For use in dogs only – not for cats or other species
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• Not for use in dogs less than 12 months of age
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• Do not use in dogs with serious infections
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• Not recommended for breeding, pregnant, or lactating dogs
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• May increase susceptibility to infection (including demodicosis) and may exacerbate neoplastic conditions
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• Monitor dogs for development of infections or new lumps during treatment
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• Most common side effects: vomiting, diarrhea, lethargy, anorexia
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• Keep out of reach of children and other animals
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Prescription Required: This is a prescription-only medicine. A valid veterinary prescription is required before dispensing.

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Storage

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Store at controlled room temperature (20–25°C). Protect from moisture. Keep the bottle tightly closed. Half tablets should be used within 14 days when stored in the original container.

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Why Choose Apoquel?

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Apoquel has been prescribed for millions of dogs and is trusted by veterinarians as a first-line treatment for allergic itch. It offers a steroid-sparing alternative that provides fast, reliable relief so your dog can stop scratching, licking, and chewing and return to a more comfortable life.

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Always follow your veterinarian’s instructions regarding dose, duration, and monitoring. Regular check-ups are recommended during long-term therapy